diff --git a/doc/guides/prog_guide/vhost_lib.rst b/doc/guides/prog_guide/vhost_lib.rst
index 05c42c9b11..c3beda23d9 100644
--- a/doc/guides/prog_guide/vhost_lib.rst
+++ b/doc/guides/prog_guide/vhost_lib.rst
@@ -118,6 +118,15 @@ The following is an overview of some key Vhost API functions:
 
     It is disabled by default.
 
+  - ``RTE_VHOST_USER_ASYNC_USE_VFIO``
+
+    In asynchronous data path, vhost liarary is not aware of which driver
+    (igb_uio/vfio) the DMA device is bound to. Application should pass
+    this flag to tell vhost library whether IOMMU should be programmed
+    for guest memory.
+
+    It is disabled by default.
+
   - ``RTE_VHOST_USER_NET_COMPLIANT_OL_FLAGS``
 
     Since v16.04, the vhost library forwards checksum and gso requests for
diff --git a/lib/vhost/rte_vhost.h b/lib/vhost/rte_vhost.h
index 8d875e9322..a766ea7b6b 100644
--- a/lib/vhost/rte_vhost.h
+++ b/lib/vhost/rte_vhost.h
@@ -37,6 +37,7 @@ extern "C" {
 #define RTE_VHOST_USER_LINEARBUF_SUPPORT	(1ULL << 6)
 #define RTE_VHOST_USER_ASYNC_COPY	(1ULL << 7)
 #define RTE_VHOST_USER_NET_COMPLIANT_OL_FLAGS	(1ULL << 8)
+#define RTE_VHOST_USER_ASYNC_USE_VFIO	(1ULL << 9)
 
 /* Features. */
 #ifndef VIRTIO_NET_F_GUEST_ANNOUNCE
diff --git a/lib/vhost/socket.c b/lib/vhost/socket.c
index 5d0d728d52..77c722c86b 100644
--- a/lib/vhost/socket.c
+++ b/lib/vhost/socket.c
@@ -42,6 +42,7 @@ struct vhost_user_socket {
 	bool extbuf;
 	bool linearbuf;
 	bool async_copy;
+	bool async_use_vfio;
 	bool net_compliant_ol_flags;
 
 	/*
@@ -243,6 +244,13 @@ vhost_user_add_connection(int fd, struct vhost_user_socket *vsocket)
 			dev->async_copy = 1;
 	}
 
+	if (vsocket->async_use_vfio) {
+		dev = get_device(vid);
+
+		if (dev)
+			dev->async_use_vfio = 1;
+	}
+
 	VHOST_LOG_CONFIG(INFO, "new device, handle is %d\n", vid);
 
 	if (vsocket->notify_ops->new_connection) {
@@ -879,6 +887,7 @@ rte_vhost_driver_register(const char *path, uint64_t flags)
 	vsocket->extbuf = flags & RTE_VHOST_USER_EXTBUF_SUPPORT;
 	vsocket->linearbuf = flags & RTE_VHOST_USER_LINEARBUF_SUPPORT;
 	vsocket->async_copy = flags & RTE_VHOST_USER_ASYNC_COPY;
+	vsocket->async_use_vfio = flags & RTE_VHOST_USER_ASYNC_USE_VFIO;
 	vsocket->net_compliant_ol_flags = flags & RTE_VHOST_USER_NET_COMPLIANT_OL_FLAGS;
 
 	if (vsocket->async_copy &&
diff --git a/lib/vhost/vhost.h b/lib/vhost/vhost.h
index 8078ddff79..fb775ce4ed 100644
--- a/lib/vhost/vhost.h
+++ b/lib/vhost/vhost.h
@@ -370,6 +370,7 @@ struct virtio_net {
 	int16_t			broadcast_rarp;
 	uint32_t		nr_vring;
 	int			async_copy;
+	int			async_use_vfio;
 	int			extbuf;
 	int			linearbuf;
 	struct vhost_virtqueue	*virtqueue[VHOST_MAX_QUEUE_PAIRS * 2];
diff --git a/lib/vhost/vhost_user.c b/lib/vhost/vhost_user.c
index 8f0eba6412..72459e192f 100644
--- a/lib/vhost/vhost_user.c
+++ b/lib/vhost/vhost_user.c
@@ -45,6 +45,7 @@
 #include <rte_common.h>
 #include <rte_malloc.h>
 #include <rte_log.h>
+#include <rte_vfio.h>
 
 #include "iotlb.h"
 #include "vhost.h"
@@ -141,6 +142,36 @@ get_blk_size(int fd)
 	return ret == -1 ? (uint64_t)-1 : (uint64_t)stat.st_blksize;
 }
 
+static int
+async_dma_map(struct rte_vhost_mem_region *region, bool do_map)
+{
+	int ret = 0;
+	uint64_t host_iova;
+	host_iova = rte_mem_virt2iova((void *)(uintptr_t)region->host_user_addr);
+	if (do_map) {
+		/* Add mapped region into the default container of DPDK. */
+		ret = rte_vfio_container_dma_map(RTE_VFIO_DEFAULT_CONTAINER_FD,
+						 region->host_user_addr,
+						 host_iova,
+						 region->size);
+		if (ret) {
+			VHOST_LOG_CONFIG(ERR, "DMA engine map failed\n");
+			return ret;
+		}
+	} else {
+		/* Remove mapped region from the default container of DPDK. */
+		ret = rte_vfio_container_dma_unmap(RTE_VFIO_DEFAULT_CONTAINER_FD,
+						   region->host_user_addr,
+						   host_iova,
+						   region->size);
+		if (ret) {
+			VHOST_LOG_CONFIG(ERR, "DMA engine unmap failed\n");
+			return ret;
+		}
+	}
+	return ret;
+}
+
 static void
 free_mem_region(struct virtio_net *dev)
 {
@@ -155,6 +186,9 @@ free_mem_region(struct virtio_net *dev)
 		if (reg->host_user_addr) {
 			munmap(reg->mmap_addr, reg->mmap_size);
 			close(reg->fd);
+
+			if (dev->async_copy && dev->async_use_vfio)
+				async_dma_map(reg, false);
 		}
 	}
 }
@@ -1105,6 +1139,7 @@ vhost_user_mmap_region(struct virtio_net *dev,
 	uint64_t mmap_size;
 	uint64_t alignment;
 	int populate;
+	int ret;
 
 	/* Check for memory_size + mmap_offset overflow */
 	if (mmap_offset >= -region->size) {
@@ -1158,13 +1193,22 @@ vhost_user_mmap_region(struct virtio_net *dev,
 	region->mmap_size = mmap_size;
 	region->host_user_addr = (uint64_t)(uintptr_t)mmap_addr + mmap_offset;
 
-	if (dev->async_copy)
+	if (dev->async_copy) {
 		if (add_guest_pages(dev, region, alignment) < 0) {
 			VHOST_LOG_CONFIG(ERR,
 					"adding guest pages to region failed.\n");
 			return -1;
 		}
 
+		if (dev->async_use_vfio) {
+			ret = async_dma_map(region, true);
+			if (ret) {
+				VHOST_LOG_CONFIG(ERR, "Configure IOMMU for DMA engine failed\n");
+				return -1;
+			}
+		}
+	}
+
 	VHOST_LOG_CONFIG(INFO,
 			"guest memory region size: 0x%" PRIx64 "\n"
 			"\t guest physical addr: 0x%" PRIx64 "\n"
